| Transactions |
| Date | Team | Player | Type | OthTm | EffDate | When |
| 2/2/2016 | FAR | Blanco,A | Acquired via trade | HUD | | After |
| 2/2/2016 | FAR | Walker,N | Traded away | HUD | | After |
| 2/2/2016 | HUD | Blanco,A | Traded away | FAR | | After |
| 2/2/2016 | HUD | Walker,N | Acquired via trade | FAR | | After |
| 4/14/2016 | FAR | Taylor,M | Promoted to active roster | | | Before |
| 4/14/2016 | MIS | Martinez,N | Signed | | | Before |
| 4/14/2016 | MIS | Martinez,N | Demoted to reserve roster | | | Before |
| 4/17/2016 | ALB | Paxton | Promoted to active roster | | | Before |
| 4/18/2016 | FAR | Taylor,M | Demoted to reserve roster | | | Before |
| 4/18/2016 | TUC | Aybar | Signed | | | Before |
| 4/18/2016 | TUC | Blanco,G | Demoted to reserve roster | | | Before |
| 4/18/2016 | TUC | Blanco,G | Promoted to active roster | | | Before |
| 4/18/2016 | TUC | Gose | Promoted to active roster | | | Before |
| 4/18/2016 | TUC | Headley | Released | | | Before |
| 4/18/2016 | TUC | Heaney | Promoted to active roster | | | Before |
| 4/18/2016 | TUC | Samardzija | Demoted to reserve roster | | | Before |
| 4/19/2016 | BUF | Souza | Promoted to active roster | | | Before |
| 4/22/2016 | TUC | Blanco,G | Demoted to reserve roster | | | Before |
| 4/22/2016 | TUC | Ramirez,H | Demoted to reserve roster | | | Before |
| 4/22/2016 | TUC | Soler | Promoted to active roster | | | Before |
| 4/25/2016 | SJ | Perez,W | Signed | | | Before |
| 4/25/2016 | SJ | Perez,W | Demoted to reserve roster | | | Before |
| 4/25/2016 | SJ | Ramirez,Ne | Promoted to active roster | | | Before |
| 4/28/2016 | FAR | Teheran | Promoted to active roster | | | Before |
| 4/28/2016 | HAR | Sandoval | Released | | | Before |
| 4/28/2016 | HAR | Sardinas | Signed | | | Before |
| 4/28/2016 | HAR | Sardinas | Demoted to reserve roster | | | Before |
| 4/28/2016 | MIA | Locke | Promoted to active roster | | | Before |
| 5/5/2016 | IND | Span | Promoted to active roster | | | Before |
| 5/17/2016 | FAR | Teheran | Demoted to reserve roster | | | Before |
| 5/20/2016 | FAR | Teheran | Promoted to active roster | | | Before |
| 5/28/2016 | FAR | Taylor,M | Promoted to active roster | | | Before |
| 5/30/2016 | FAR | Teheran | Demoted to reserve roster | | | Before |
| 6/3/2016 | IND | Span | Demoted to reserve roster | | | Before |
| 6/8/2016 | FAR | Garcia,Ad | Promoted to active roster | | | Before |
| 6/13/2016 | BUF | Iglesias,R | Promoted to active roster | | | Before |
| 6/13/2016 | FAR | Garcia,Ad | Demoted to reserve roster | | | Before |
| 6/13/2016 | FAR | Taylor,M | Demoted to reserve roster | | | Before |
| 6/15/2016 | FAR | Garcia,Ad | Promoted to active roster | | | Before |
| 6/15/2016 | IND | Burnett | Promoted to active roster | | | Before |
| 6/21/2016 | MIA | Locke | Demoted to reserve roster | | | Before |
| 6/21/2016 | MIA | Nicolino | Promoted to active roster | | | Before |
| 6/21/2016 | MIA | Peavy | Demoted to reserve roster | | | Before |
| 6/30/2016 | SJ | Bolsinger | Promoted to active roster | | | Before |
| 7/1/2016 | FAR | Santana,Do | Promoted to active roster | | | Before |
| 7/2/2016 | BUF | Peralta,Jh | Demoted to reserve roster | | | Before |
| 7/2/2016 | BUF | Velasquez | Promoted to active roster | | | Before |
| 7/3/2016 | IND | Burnett | Demoted to reserve roster | | | Before |
| 7/6/2016 | FAR | Teheran | Promoted to active roster | | | Before |
| 7/10/2016 | FAR | Santana,Do | Demoted to reserve roster | | | Before |
| 7/14/2016 | FAR | Santana,Do | Promoted to active roster | | | Before |
| 7/14/2016 | SJ | Bolsinger | Demoted to reserve roster | | | Before |
| 7/20/2016 | FAR | Garcia,Ad | Demoted to reserve roster | | | Before |
| 7/20/2016 | FAR | Santana,Do | Demoted to reserve roster | | | Before |
| 7/20/2016 | FAR | Teheran | Demoted to reserve roster | | | Before |
| 7/20/2016 | IND | Burnett | Promoted to active roster | | | Before |
| 7/20/2016 | IND | Span | Promoted to active roster | | | Before |
| 7/23/2016 | FAR | Archer | Acquired via trade | FL | | After |
| 7/23/2016 | FAR | Crawford,B | Acquired via trade | FL | | After |
| 7/23/2016 | FAR | Hardy,J | Traded away | FL | | After |
| 7/23/2016 | FAR | Young,CR | Traded away | FL | | After |
| 7/23/2016 | FL | Archer | Traded away | FAR | | After |
| 7/23/2016 | FL | Crawford,B | Traded away | FAR | | After |
| 7/23/2016 | FL | Hardy,J | Acquired via trade | FAR | | After |
| 7/23/2016 | FL | Young,CR | Acquired via trade | FAR | | After |
| 7/27/2016 | IND | Altherr | Promoted to active roster | | | Before |
| 7/29/2016 | IND | Burnett | Demoted to reserve roster | | | Before |
| 7/31/2016 | FAR | Garcia,Ad | Traded away | HUD | | After |
| 7/31/2016 | FAR | Granderson | Acquired via trade | HUD | | After |
| 7/31/2016 | HUD | Garcia,Ad | Acquired via trade | FAR | | After |
| 7/31/2016 | HUD | Granderson | Traded away | FAR | | After |
| 8/1/2016 | FAR | Alonso | Demoted to reserve roster | | | Before |
| 8/13/2016 | BUF | Iglesias,R | Demoted to reserve roster | | | Before |
| 8/13/2016 | BUF | Velasquez | Demoted to reserve roster | | | Before |
| 8/18/2016 | FAR | Karns | Demoted to reserve roster | | | Before |
| 8/18/2016 | FAR | Santana,Do | Promoted to active roster | | | Before |
| 8/21/2016 | ALB | Singleton | Demoted to reserve roster | | | Before |
| 8/21/2016 | HUD | Boxberger | Promoted to active roster | | | Before |
| 8/21/2016 | IND | Altherr | Demoted to reserve roster | | | Before |
| 8/29/2016 | FAR | Karns | Promoted to active roster | | | Before |
| 8/31/2016 | BUF | Iglesias,R | Promoted to active roster | | | Before |
| 9/4/2016 | FAR | Alonso | Promoted to active roster | | | Before |
| 9/4/2016 | FAR | Taylor,M | Promoted to active roster | | | Before |
| 9/4/2016 | TUC | Olivera | Demoted to reserve roster | | | Before |
| 9/4/2016 | TUC | Ramirez,H | Promoted to active roster | | | Before |
| 9/8/2016 | FAR | Karns | Demoted to reserve roster | | | Before |
| 9/8/2016 | FAR | Teheran | Promoted to active roster | | | Before |
| 9/12/2016 | FAR | Teheran | Demoted to reserve roster | | | Before |
| 9/12/2016 | FAR | Watson | Demoted to reserve roster | | | Before |
| 9/20/2016 | BUF | Peralta,Jh | Promoted to active roster | | | Before |
| 9/20/2016 | BUF | Souza | Demoted to reserve roster | | | Before |